Rheumatology International

, Volume 24, Issue 3, pp 141–146

Ventricular function abnormalities in active rheumatoid arthritis: a Doppler echocardiographic study

Authors

    • Department of Physical Medicine and RehabilitationMeram Medical School of Selcuk University
    • Selçuk Universitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon
  • Ahmet Temizhan
    • Department of CardiologyMeram Medical School of Selcuk University
  • Hatice Ugurlu
    • Department of Physical Medicine and RehabilitationMeram Medical School of Selcuk University
  • Ayse Ozdemir
    • Department of CardiologyMeram Medical School of Selcuk University
  • Mehmet Yazici
    • Department of CardiologyMeram Medical School of Selcuk University
Original Article

DOI: 10.1007/s00296-003-0342-z

Cite this article as:
Levendoglu, F., Temizhan, A., Ugurlu, H. et al. Rheumatol Int (2004) 24: 141. doi:10.1007/s00296-003-0342-z

Abstract

Objective

The aim of the present study was to evaluate cardiac involvement in patients with active rheumatoid arthritis (RA).

Methods

Forty patients with active RA participated. All were submitted to standard Doppler echocardiography and myocardial performance index (MPI) grading.

Results

There were left and right ventricular diastolic function abnormalities in RA patients. Left ventricular MPI was also significantly higher than in controls (P<0.05). A relationship was found between left ventricular early diastolic (E)/atrial (A) flow velocities (E/A ratio), isovolumic relaxation time (IRT), and disease duration (r=−0.47 and P=0.002, r=0.618 and P=0.000, respectively).

Conclusion

Diastolic function was impaired in both ventricles in patients with active RA. There was a direct relationship between some of the parameters of left ventricular diastolic function and disease duration as well. These findings suggest a subclinical myocardial involvement in RA patients.

Keywords

Cardiac involvement Doppler echocardiography Myocardial performance index Rheumatoid arthritis

Copyright information

© Springer-Verlag 2003