Current Genetics

, Volume 41, Issue 6, pp 367–378

The genetic complexity of chitin synthesis in fungi

  • Cesar Roncero
Review Article

DOI: 10.1007/s00294-002-0318-7

Cite this article as:
Roncero, C. Curr Genet (2002) 41: 367. doi:10.1007/s00294-002-0318-7


Chitin synthesis is a process maintained across the fungal kingdom that, thanks to the power of genetic manipulation of yeast cells, is now beginning to be understood. Chitin synthesis is based on the regulation of distinct chitin synthase isoenzymes whose number ranges from one in Schizosaccharomyces pombe to seven in some filamentous fungi, such as Aspergillus fumigatus. This high diversity makes it difficult to find a unique model of regulation. However, the results available suggest common themes in regulation. The arrival of the genomic era, together with the development of fungal genetic technology should allow experimental approaches to this process.

Cell wall Chitin Fungi Chitin synthases CHS genes

Copyright information

© Springer-Verlag 2002

Authors and Affiliations

  • Cesar Roncero
    • 1
  1. 1.Departamento de Microbiología y Genética, Edificio Departamental R-219, Consejo Superior de Investigaciones Científicas/Universidad de Salamanca, Avenida Campo Charro s/n, 37007 Salamanca, Spain
  2. 2.Instituto de Microbiología Bioquímica, CSIC/Universidad de Salamanca, 37007 Salamanca, Spain