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Differenzialdiagnostik ovarieller Metastasen

Differential diagnosis of ovarian metastases

  • Schwerpunkt: Ovarialtumoren
  • Published:
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Zusammenfassung

Metastasen sind mit 7–10% aller malignen Ovarialtumoren ein praxisrelevantes Problem. Ihre Erkennung ist schwierig, da die morphologische Bandbreite primärer ovarieller Tumoren sehr groß ist, aber auch, weil Metastasen einen organtypischen Tumor perfekt imitieren können. Die richtige Diagnose ist aber therapeutisch entscheidend. Deswegen sollte bei jedem morphologisch ungewöhnlichen Ovarialtumor an eine Metastase gedacht werden. Aber auch auf den ersten Blick als Primärtumor erscheinende muzinöse und endometrioide Tumoren können metastatischer Herkunft sein. Durch Kenntnis der Krankengeschichte und immunhistochemische Untersuchungen ist in der Regel eine korrekte Diagnose möglich.

Abstract

Ovarian metastases comprise 7–10% of all malignant ovarian tumors. The detection of ovarian metastases is difficult because primary ovarian tumors are a morphologically very heterogeneous group, and metastases can simulate an primary ovarian tumor perfectly. A correct diagnosis, however, is most important in order to avoid an unnecessary and ineffective chemotherapy. Therefore, every morphologically unusual ovarian tumor should raise doubts. In addition, mucinous and endometrioid tumors may also be metastatic in nature. Immunohistochemistry, as well as knowledge on the patient’s history, will clarify most of the suspicious cases.

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Hauptmann, S. Differenzialdiagnostik ovarieller Metastasen. Pathologe 28, 215–221 (2007). https://doi.org/10.1007/s00292-007-0906-x

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