Current Microbiology

, Volume 33, Issue 1, pp 1–5

In Vitro Evaluation of the Efficacy of a Silver-Coated Catheter

  • Manal M.  Gabriel
  • Mary S.  Mayo
  • Lauren L.  May
  • Robert B.  Simmons
  • Donald G.  Ahearn

DOI: 10.1007/s002849900064

Cite this article as:
Gabriel, M., Mayo, M., May, L. et al. Curr Microbiol (1996) 33: 1. doi:10.1007/s002849900064

Abstract.

Bacteria commonly associated with nosocomial urinary tract infections were examined in vitro for their relative adherence to latex, 100% silicone-, hydrogel-coated latex-, and hydrogel/silver-coated latex urinary catheters. Degrees of adherence within 2 h were determined with cells radiolabeled with leucine. Adherence was greatest and equivalent on silicone and latex catheters. Adherence of four strains of Escherichia coli to the hydrogel/silver-coated catheter was decreased by 50% to 99% in comparison with the other catheters. Repeat testing with strains of E. coli and Pseudomonas aeruginosa with over 50 catheters demonstrated a consistency in the inhibition. The hydrophilic coating of the catheter appeared to be primary in the decreased adherence phenomenon followed by a secondary biocidal effect of the silver ion.

Copyright information

© Springer-Verlag New York Inc. 1996

Authors and Affiliations

  • Manal M.  Gabriel
    • 1
  • Mary S.  Mayo
    • 2
  • Lauren L.  May
    • 1
  • Robert B.  Simmons
    • 1
  • Donald G.  Ahearn
    • 1
  1. 1.Biology Department, Georgia State University, Atlanta, GA 30302-4010, USA US
  2. 2.C.R. Bard, Inc., Covington, GA 30209, USA US