Current Microbiology

, Volume 55, Issue 5, pp 409–412

Inhibitory Activity of Probiotic Bacillus subtilis UTM 126 Against Vibrio Species Confers Protection Against Vibriosis in Juvenile Shrimp (Litopenaeus vannamei)


DOI: 10.1007/s00284-007-9000-0

Cite this article as:
Balcázar, J.L. & Rojas-Luna, T. Curr Microbiol (2007) 55: 409. doi:10.1007/s00284-007-9000-0


The bacterial strain Bacillus subtilis UTM 126 produced antimicrobial activity against pathogenic Vibrio species, including V. alginolyticus, V. parahaemolyticus, and V. harveyi. The probiotic effect of B. subtilis was tested by feeding juvenile shrimp (Litopenaeus vannamei) food supplemented with B. subtilis (105 CFU/g) for 28 days before an immersion challenge with V. harveyi at 105 CFU/mL for 24 h. The treatment with B. subtilis UTM 126 decreased final mortality to 18.25%, compared with 51.75% in the control group. Bacillus subtilis UTM 126 has potential applications for controlling pathogenic V. harveyi in shrimp aquaculture.


Pathogenic controlProbioticShrimpVibriosis

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  1. 1.Laboratory of Fish Pathology, Faculty of Veterinary SciencesUniversity of ZaragozaZaragozaSpain
  2. 2.Faculty of AquacultureTechnical University of MachalaMachalaEcuador