Annals of Hematology

, Volume 85, Issue 2, pp 126–128

Prothrombin G20210A gene variant is not associated with idiopathic portal vein thrombosis in an area endemic for portal vein thrombosis

Original Article

DOI: 10.1007/s00277-005-0020-1

Cite this article as:
Koshy, A. & Jeyakumari, M. Ann Hematol (2006) 85: 126. doi:10.1007/s00277-005-0020-1

Abstract

Prothrombin G20210A gene variant has been found in 0–23% of patients with portal vein thrombosis (PVT). This wide variation makes it difficult to assess the importance of prothrombin G20210A gene variant as a predisposing factor for PVT. In this study from South India, none of the patients with idiopathic PVT (0/38) or any of the controls (0/46) had prothrombin G20210A gene variant. Prothrombin G20210A gene variant does not contribute to the development of PVT in India.

Keywords

Portal hypertension Human polymorphism Genetics 

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  1. 1.Department of GastroenterologyInstitute of Population Health and Clinical Research, St. John’s Medical College HospitalBangaloreIndia
  2. 2.Molecular Biology UnitInstitute of Population Health and Clinical Research, St. John’s Medical College HospitalBangaloreIndia

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