CardioVascular and Interventional Radiology

, Volume 26, Issue 1, pp 19–26

Percutaneous Management of Occlusive Arterial Disease Associated with Vasculitis: A Single Center Experience

  • M. Both
  • T. Jahnke
  • E. Reinhold-Keller
  • M. Reuter
  • J. Grimm
  • J. Biederer
  • J. Brossmann
  • W.L. Gross
  • M. Heller
  • S. Mueller-Huelsbeck

DOI: 10.1007/s00270-002-2610-9

Cite this article as:
Both, M., Jahnke, T., Reinhold-Keller, E. et al. CVIR (2003) 26: 19. doi:10.1007/s00270-002-2610-9

The purpose of this study was to evaluate the safety and effectiveness of percutaneous transluminal angioplasty for occlusive arterial disease associated with vasculitis. Eleven patients (10 women, 1 man; ages 35–82 years) with the diagnosis of vasculitis of the large vessels underwent interventional treatment during intraarterial angiography. The causes included giant cell arteritis (n = 8) and Takayasu arteritis (n = 3). Thirty-three occlusive lesions (including brachiocephalic and renal arteries, and arteries of upper and lower extremities) were treated with balloon angioplasty and/or stent placement. Follow-up included clinical examination, angiography, and color duplex ultrasound. Technical success was 100% (25/25) for stenoses and 50% (4/8) for occlusive lesions, representing all lesions combined from different anatomic locations. Dissection (n = 3) and arterial rupture with retroperitoneal hematoma (n = 1) was found in three patients. During follow-up (mean 12 months), restenoses (n = 8) and re-restenoses (n = 1) occurred in 8 vascular areas. Three of these lesions were treated with repeated PTA (n = 4). The cumulative primary clinical success rate was 67.6%, cumulative secondary success rate 74.4%, and cumulative tertiary success rate 75.9%. Interventional therapy in systemic vasculitis provides promising results in technical success rates and followup. Angioplasty may result in arterial injury, but the rate of complications is low.

Copyright information

© Springer-Verlag New York, Inc. 2003

Authors and Affiliations

  • M. Both
    • 1
  • T. Jahnke
    • 1
  • E. Reinhold-Keller
    • 2
  • M. Reuter
    • 1
  • J. Grimm
    • 1
  • J. Biederer
    • 1
  • J. Brossmann
    • 1
  • W.L. Gross
    • 2
  • M. Heller
    • 1
  • S. Mueller-Huelsbeck
    • 1
  1. 1.Department of Radiology, Christian-Albrechts-University of Kiel, Kiel, GermanyGERMANY
  2. 2.Department of Rheumatology, University of Luebeck, Rheumaklinik Bad Bramstedt, GermanyGERMANY