World Journal of Surgery

, Volume 33, Issue 10, pp 1983–1988

Obesity, Gut Hormones, and Bariatric Surgery


DOI: 10.1007/s00268-009-0080-9

Cite this article as:
Pournaras, D.J. & le Roux, C.W. World J Surg (2009) 33: 1983. doi:10.1007/s00268-009-0080-9


Obesity is becoming the healthcare epidemic of this century. Bariatric surgery is the only effective treatment for morbid obesity. Gut hormones are key players in the metabolic mechanisms causing obesity. In this review we explore the role of these hormones as facilitators of appetite control and weight loss after bariatric surgery, and we describe the now established gut–brain axis.

Copyright information

© Société Internationale de Chirurgie 2009

Authors and Affiliations

  1. 1.Department of Bariatric SurgeryMusgrove Park HospitalTauntonUK
  2. 2.Department of Investigative MedicineImperial College LondonLondonUK
  3. 3.Department of Investigative MedicineHammersmith Hospital, Imperial College LondonLondonUK

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