World Journal of Surgery

, Volume 29, Issue 9, pp 1139–1142

Abdominal Angina in Patients with a Midgut Carcinoid, a Sign of Severe Pathology

  • Harry de Vries
  • Rob T. M. Wijffels
  • Pax H. B. Willemse
  • René C. J. Verschueren
  • Ido P. Kema
  • Arend Karrenbeld
  • Ted R. Prins
  • Elisabeth G. E. de Vries
Article

DOI: 10.1007/s00268-005-7825-x

Cite this article as:
de Vries, H., Wijffels, R.T.M., Willemse, P.H.B. et al. World J. Surg. (2005) 29: 1139. doi:10.1007/s00268-005-7825-x

Abstract

In 36 consecutive patients with a foregut carcinoid with extensive local tumor growth and liver metastases with a carcinoid syndrome, six patients had complaints of postprandial abdominal pain and attacks of subileus based on segmental intestinal ischemia. A diagnosis of abdominal angina was supported by a positive response to nitroglycerin in two and ischemia of the ileum demonstrated by angiography in two other patients. Complaints were reduced in all patients after surgery. Histopathology of the resected small bowel specimens showed elastic vascular sclerosis in three patients and ischemic changes in three other patients, confirming the clinical diagnosis. Resection of ischemic bowel can provide relief in patients with segmental intestinal ischemia caused by carcinoid-induced vascular sclerosis.

Copyright information

© Société Internationale de Chirurgie 2005

Authors and Affiliations

  • Harry de Vries
    • 1
  • Rob T. M. Wijffels
    • 1
  • Pax H. B. Willemse
    • 2
  • René C. J. Verschueren
    • 1
  • Ido P. Kema
    • 3
  • Arend Karrenbeld
    • 3
  • Ted R. Prins
    • 4
  • Elisabeth G. E. de Vries
    • 2
  1. 1.Department of Surgery University Medical Center GroningenGroningenThe Netherlands
  2. 2.Department of Medical OncologyUniversity Medical Center GroningenGroningenThe Netherlands
  3. 3.Department of Pathology and Laboratory MedicineUniversity Medical Center GroningenGroningenThe Netherlands
  4. 4.Department of RadiologyUniversity Medical Center GroningenGroningenThe Netherlands