International Orthopaedics

, Volume 35, Issue 9, pp 1349–1358

Percutaneous vertebroplasty versus balloon kyphoplasty for treatment of osteoporotic vertebral compression fracture: a meta-analysis of randomised and non-randomised controlled trials

  • Shiliang Han
  • Shuanglin Wan
  • Lei Ning
  • Yongjun Tong
  • Jianfeng Zhang
  • Shunwu Fan
Review

DOI: 10.1007/s00264-011-1283-x

Cite this article as:
Han, S., Wan, S., Ning, L. et al. International Orthopaedics (SICOT) (2011) 35: 1349. doi:10.1007/s00264-011-1283-x

Abstract

Purpose

There is still debate over whether vertebroplasty (VP) or kyphoplasty (KP) is superior for the treatment of osteoporosis vertebral compression fractures (VCFs). We performed a systematic review and meta-analysis of randomised and non-randomised controlled trials comparing VP with KP to reach a relatively conclusive answer.

Methods

We searched computerised databases comparing efficacy and safety of VP and KP in osteoporotic fractures. These trials reported pain relief (Visual Analogue Scale), disability (Oswestry disability score) and complications (i.e., cement leakage, incident fractures) as the primary outcome.

Results

Eight studies involving 848 patients were identified. The outcome showed that VP is more effective in the short-term (no more than seven days) pain relief. Kyphoplasty had a superior capability for intermediate-term (around three months) functional improvement. As for long-term pain relief and functional improvement, there is no significant difference between these two interventions. Consistently, both interventions have similar risk for subsequent fracture and cement leakage.

Conclusion

Thus considering the higher cost of the KP procedure, we recommend VP over KP for the treatment of osteoporotic VCFs.

Abbreviation

VCFs

Vertebral compression fractures

VP

Vertebroplasty

KP

Kyphoplasty

RCTs

Randomised controlled trials

NRTs

Non-randomised controlled trials

CCTs

Clinical controlled trials

VAS

Visual analog scale

ODI

Oswestry disability score

RR

Relative risks

WMD

Weighted mean difference

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Shiliang Han
    • 1
  • Shuanglin Wan
    • 1
  • Lei Ning
    • 1
  • Yongjun Tong
    • 1
  • Jianfeng Zhang
    • 1
  • Shunwu Fan
    • 1
  1. 1.Department of Orthopaedics, Sir Run Run Shaw HospitalSchool of Medicine, Zhejiang UniversityZhejiangChina