The role of CD4+ T cell help in cancer immunity and the formulation of novel cancer vaccines
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- Assudani, D.P., Horton, R.B.V., Mathieu, M.G. et al. Cancer Immunol Immunother (2007) 56: 70. doi:10.1007/s00262-006-0154-6
Recent years have seen the unprecedented surge of interest in the role of CD4+ T cells and the role they play in the development of the immune response. In this symposium review, we examine the evidence for this and discuss their functions, particularly in respect to the cancer immunology, including CD4+CD25+ cells (Treg).