Article

Abdominal Imaging

, Volume 37, Issue 2, pp 261-274

Immunological diseases of the pancreatico-hepatobiliary system: update on etiopathogenesis and cross-sectional imaging findings

  • Deepak GargAffiliated withDepartment of Radiology, University of Texas Health Science Center
  • , Arpit NagarAffiliated withDepartment of Radiology, Ohio State University Medical Center
  • , Shaile PhilipsAffiliated withDepartment of Radiology, University of Texas Health Science Center
  • , Naoki TakahashiAffiliated withDepartment of Radiology, Mayo Clinic
  • , Srinivasa R. PrasadAffiliated withDepartment of Radiology, University of Texas MD Anderson Cancer Center Email author 
  • , Alampady K. ShanbhogueAffiliated withDepartment of Radiology, University of Texas Health Science Center
  • , Dushyant V. SahaniAffiliated withDepartment of Radiology, Massachusetts General Hospital

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Abstract

Immunological diseases of the hepatobiliary system and the pancreas include a broad spectrum of disorders that manifest characteristic histopathology/serology and variable clinical features and imaging findings. Recent studies have thrown fresh light on the complex role of genetics and autoimmunity in the pathogenesis and natural history of these diverse disorders that include autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, IgG4-related cholangitis, overlap/outlier syndromes, and autoimmune pancreatitis.

Key words

Autoimmune hepatitis Primary biliary cirrhosis Primary sclerosing cholangitis IgG-4-related disease Computed tomography Magnetic resonance imaging