Abdominal Imaging

, Volume 34, Issue 4, pp 441–447

Detecting recurrence of gastric cancer: the value of FDG PET/CT

Authors

  • Min Jung Park
    • Department of Radiology and Center for Imaging Science, Samsung Medical CenterSungkyunkwan University School of Medicine
    • Department of Radiology and Center for Imaging Science, Samsung Medical CenterSungkyunkwan University School of Medicine
  • Hyo K. Lim
    • Department of Radiology and Center for Imaging Science, Samsung Medical CenterSungkyunkwan University School of Medicine
  • Ko Woon Park
    • Department of Radiology and Center for Imaging Science, Samsung Medical CenterSungkyunkwan University School of Medicine
  • Joon Young Choi
    • Department of Nuclear Medicine, Samsung Medical CenterSungkyunkwan University School of Medicine
  • Byung-Tae Kim
    • Department of Nuclear Medicine, Samsung Medical CenterSungkyunkwan University School of Medicine
Article

DOI: 10.1007/s00261-008-9424-4

Cite this article as:
Park, M.J., Lee, W.J., Lim, H.K. et al. Abdom Imaging (2009) 34: 441. doi:10.1007/s00261-008-9424-4

Abstract

Purpose

In order to assess the diagnostic performance of Positron emission tomography/Computed tomography (PET/CT) for detecting recurrence in gastric cancer patients with clinical or radiologic suspicion of recurrence after surgical resection.

Materials and methods

Over a 4-year period, 105 post-operative patients with gastric cancer, who underwent PET/CT due to clinical or radiologic suspicion of recurrence during follow-up, were collected after confirming their PET/CT findings. The number and site of positive FDG uptake were retrospectively analyzed, and were correlated with the final diagnosis, by calculating the diagnostic values and assessing the causes of misdiagnosis.

Results

Of all 105 patients, 75 patients were confirmed to have true recurrence with 108 recurrence sites. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy for diagnosing true recurrence on a per-person basis were 75%, 77%, 89%, 55%, and 75%, respectively. On a per-lesion basis, 75 (69%) of 108 true recurrences showed positive FDG uptake, while 75 (89%) of 84 positive FDG uptake was confirmed to have true recurrence.

Conclusion

PET/CT was relatively accurate in detecting recurrence in post-operative patients with gastric cancer. Moreover, PET/CT might be helpful in confirming the presence of recurrence particularly in patients who were highly suspicious of recurrence, because of its high positive predictability.

Keywords

StomachCancerRecurrencePositron emission tomographyPET/CT

Copyright information

© Springer Science+Business Media, LLC 2008