Article

Abdominal Imaging

, Volume 34, Issue 1, pp 75-80

Resectability of pancreatic adenocarcinoma: assessment using multidetector-row computed tomography with multiplanar reformations

  • Elena ManakAffiliated withInstitute for Diagnostic Radiology, Friedrich-Alexander University of Erlangen-Nuremberg Email author 
  • , Susanne MerkelAffiliated withDepartment of Surgery, Friedrich-Alexander University of Erlangen-Nuremberg
  • , Peter KleinAffiliated withDepartment of Surgery, Friedrich-Alexander University of Erlangen-Nuremberg
  • , Thomas PapadopoulosAffiliated withDepartment of Pathology, Friedrich-Alexander University of Erlangen-Nuremberg
  • , Werner A. BautzAffiliated withInstitute for Diagnostic Radiology, Friedrich-Alexander University of Erlangen-Nuremberg
  • , Ulrich BaumAffiliated withInstitute for Diagnostic Radiology, Friedrich-Alexander University of Erlangen-Nuremberg

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

The purpose was to assess capabilities of the multidetector-row computed tomography (MDCT) with multiplanar reformations (MPR) for predicting of pancreatic adenocarcinoma resectability. Forty-eight patients deemed to have resectable pancreatic adenocarcinoma after assessment using biphasic MDCT with MPRs underwent surgery for potential tumor resection. Imaging findings were retrospectively evaluated for tumor resectability and correlated with surgical and pathological results. Curative resection was successful in 44 of 48 patients. The positive predictive value for tumor resectability made up 91% with four false-negative results. The reasons for unresectability were venous involvement (1), small liver metastases (2) and peritoneal involvement associated with small metastases to lymph nodes (1). MDCT yielded a negative predictive value of 99% (286 of 288 vessels) for detection of vascular invasion. Our results indicate the tendency towards improved prediction of resectability using MDCT compared to single-detector CT.

Keywords

Computed tomography Multidetector row Pancreatic adenocarcinoma