Abdominal Imaging

, Volume 34, Issue 1, pp 75–80

Resectability of pancreatic adenocarcinoma: assessment using multidetector-row computed tomography with multiplanar reformations

  • Elena Manak
  • Susanne Merkel
  • Peter Klein
  • Thomas Papadopoulos
  • Werner A. Bautz
  • Ulrich Baum
Article

DOI: 10.1007/s00261-007-9285-2

Cite this article as:
Manak, E., Merkel, S., Klein, P. et al. Abdom Imaging (2009) 34: 75. doi:10.1007/s00261-007-9285-2

Abstract

The purpose was to assess capabilities of the multidetector-row computed tomography (MDCT) with multiplanar reformations (MPR) for predicting of pancreatic adenocarcinoma resectability. Forty-eight patients deemed to have resectable pancreatic adenocarcinoma after assessment using biphasic MDCT with MPRs underwent surgery for potential tumor resection. Imaging findings were retrospectively evaluated for tumor resectability and correlated with surgical and pathological results. Curative resection was successful in 44 of 48 patients. The positive predictive value for tumor resectability made up 91% with four false-negative results. The reasons for unresectability were venous involvement (1), small liver metastases (2) and peritoneal involvement associated with small metastases to lymph nodes (1). MDCT yielded a negative predictive value of 99% (286 of 288 vessels) for detection of vascular invasion. Our results indicate the tendency towards improved prediction of resectability using MDCT compared to single-detector CT.

Keywords

Computed tomographyMultidetector rowPancreatic adenocarcinoma

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Elena Manak
    • 1
    • 4
  • Susanne Merkel
    • 2
  • Peter Klein
    • 2
  • Thomas Papadopoulos
    • 3
  • Werner A. Bautz
    • 1
  • Ulrich Baum
    • 1
  1. 1.Institute for Diagnostic RadiologyFriedrich-Alexander University of Erlangen-NurembergErlangenGermany
  2. 2.Department of Surgery Friedrich-Alexander University of Erlangen-NurembergErlangenGermany
  3. 3.Department of PathologyFriedrich-Alexander University of Erlangen-NurembergErlangenGermany
  4. 4.MinskBelarus