Abdominal Imaging

, Volume 32, Issue 6, pp 754–757

Paroxysmal nocturnal hemoglobinuria: complete resolution of an occluding inferior vena caval thrombus

  • Shunya Shindo
  • Shinya Motohashi
  • Shigeaki Kaga
  • Hidenori Inoue
  • Masahiko Matsumoto
  • Hiroo Shindo
Article

DOI: 10.1007/s00261-007-9184-6

Cite this article as:
Shindo, S., Motohashi, S., Kaga, S. et al. Abdom Imaging (2007) 32: 754. doi:10.1007/s00261-007-9184-6

Abstract

Paroxysmal nocturnal hemoglobinuria is a rare acquired autoimmune disease, and is frequently associated with venous thrombosis. A patient who developed thrombotic occlusion of the inferior vena cava is described. Treatment with heparin and urokinase, followed by oral anticoagulant, was effective in resolving abdominal symptoms. The venous thrombosis resolved completely, but the patient died during treatment of aplastic anemia.

Keywords

Paroxysmal nocturnal hemoglobinuria Thrombosis Inferior vena cava Thrombolytic therapy Anticoagulation Aplastic anemia 

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Shunya Shindo
    • 1
  • Shinya Motohashi
    • 1
  • Shigeaki Kaga
    • 1
  • Hidenori Inoue
    • 1
  • Masahiko Matsumoto
    • 1
  • Hiroo Shindo
    • 2
  1. 1.Second Department of Surgery, Faculty of MedicineUniversity of YamanashiChuo CityJapan
  2. 2.Department of HematologyYamanashi Prefectural Central HospitalYamanashiJapan

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