, Volume 30, Issue 1, pp 1-4
Date: 17 Nov 2004

CT colonography (virtual colonoscopy) for primary colorectal screening: challenges facing clinical implementation

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Computed tomographic colonography (CTC), also referred to as virtual colonoscopy, is a minimally invasive test for the detection of colorectal polyps. Although its initial performance characteristics for evaluating low-prevalence populations were rather disappointing [1, 2], a larger multicenter trial in asymptomatic adults subsequently showed that CTC has the potential to be an effective primary screening tool [3]. Key features in the latter study that help explain this improved performance include the use of the three-dimensional endoluminal display for primary polyp detection, oral contrast for tagging of residual fluid and stool, segmental unblinding of CTC results at optical colonoscopy (OC), and use of only multidetector CT scanners [3]. As we await further validation of this rapidly evolving technique, actual clinical implementation of primary CTC screening should proceed without delay by those who are currently able to achieve an acceptable accuracy. The need for immediate acti ...