Abdominal Imaging

, Volume 29, Issue 2, pp 203–207

Hepatocellular carcinoma in advanced liver cirrhosis: CT detection in transplant patients

Invited update

DOI: 10.1007/s00261-003-0114-y

Cite this article as:
Lim, J. & Park, C. Abdom Imaging (2004) 29: 203. doi:10.1007/s00261-003-0114-y


Computed tomography (CT) is being used as the standard pretransplantation imaging for recipients and donors in the evaluation of liver volume, liver reserve function, vascular anatomy, diagnosis of hepatocellular carcinoma and metastasis, and global information of the abdominal cavity. Whereas CT detection of hepatocellular carcinoma in noncirrhotic patients is satisfactory, detection sensitivity in severely cirrhotic patients is limited, with a reported sensitivity of 53% to 68%. Tumors smaller than 2 cm are more difficult to detect. Innumerable regenerative nodules, localized or diffuse fibrosis, arterioportal shunts, nodular surface, and distorted anatomy in end-stage liver cirrhosis make it difficult to detect small hepatocellular carcinoma. Because of the shortage of cadavers and living donors, judicious use of CT is necessary in the selection of candidates and the decision of priority for liver transplantation in patients with advanced liver cirrhosis.


Liver cirrhosis Liver neoplasms Orthotopic liver transplantation Hepatocellular carcinoma Spiral computed tomography 

Copyright information

© Springer-Verlag New York, Inc. 2004

Authors and Affiliations

  1. 1.Department of Radiology and the Center for Imaging ScienceSamsung Medical Center, Sungkyunkwan University School of Medicine, 50 IIwon-dong. Kangnam-ku. Seoul 135-710Korea
  2. 2.Department of PathologySamsung Medical Center, Sungkyunkwan University School of Medicine, 50 IIwon-dong, Kangnam-ku. Seoul 135-710Korea

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