European Journal of Nuclear Medicine

, Volume 26, Issue 12, pp 1547–1552

Fluorine-18 fluorodeoxyglucose positron emission tomography in thyroid cancer: results of a multicentre study

  • Frank Grünwald
  • Thomas Kälicke
  • Ulrich Feine
  • Roland Lietzenmayer
  • Klemens Scheidhauer
  • Markus Dietlein
  • Otmar Schober
  • Hartmut Lerch
  • Katja Brandt-Mainz
  • Wolfgang Burchert
  • Gerhard Hiltermann
  • Uwe Cremerius
  • Hans-Jürgen Biersack
Original article

DOI: 10.1007/s002590050493

Cite this article as:
Grünwald, F., Kälicke, T., Feine, U. et al. Eur J Nucl Med (1999) 26: 1547. doi:10.1007/s002590050493

n

=222) and the group with negative radioiodine scan (n=166), respectively. Specificity was 90% in the whole patient group. Sensitivity and specificity of WBS were 50% and 99%, respectively. When the results of FDG-PET and WBS were considered in combination, tumour tissue was missed in only 7%. Sensitivity and specificity of MIBI/Tl were 53% and 92%, respectively (n=117). We conclude that FDG-PET is a sensitive method in the follow-up of thyroid cancer which should be considered in all patients suffering from differentiated thyroid cancer with suspected recurrence and/or metastases, and particularly in those with elevated thyroglobulin values and negative WBS.

Key words: Thyroid cancer Fluorine-18 fluorodeoxyglucose Positron emission tomography Sestamibi Radioiodine 

Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • Frank Grünwald
    • 1
  • Thomas Kälicke
    • 1
  • Ulrich Feine
    • 2
  • Roland Lietzenmayer
    • 2
  • Klemens Scheidhauer
    • 3
  • Markus Dietlein
    • 3
  • Otmar Schober
    • 4
  • Hartmut Lerch
    • 4
  • Katja Brandt-Mainz
    • 5
  • Wolfgang Burchert
    • 6
  • Gerhard Hiltermann
    • 6
  • Uwe Cremerius
    • 7
  • Hans-Jürgen Biersack
    • 1
  1. 1.Department of Nuclear Medicine, University of Bonn, GermanyDE
  2. 2.Department of Nuclear Medicine, University of Tübingen, GermanyDE
  3. 3.Department of Nuclear Medicine, University of Cologne, GermanyDE
  4. 4.Department of Nuclear Medicine, University of Münster, GermanyDE
  5. 5.Department of Nuclear Medicine, University of Essen, GermanyDE
  6. 6.Department of Nuclear Medicine, Medical School of Hannover, GermanyDE
  7. 7.Department of Nuclear Medicine, Aachen University of Technology, GermanyDE

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