European Journal of Nuclear Medicine and Molecular Imaging

, Volume 36, Issue 4, pp 602–606

Constant ambient temperature of 24°C significantly reduces FDG uptake by brown adipose tissue in children scanned during the winter

Authors

  • Katherine A. Zukotynski
    • Department of Radiology, Division of Nuclear Medicine/PET, Children’s Hospital BostonHarvard Medical School
  • Frederic H. Fahey
    • Department of Radiology, Division of Nuclear Medicine/PET, Children’s Hospital BostonHarvard Medical School
  • Stephen Laffin
    • Department of Radiology, Division of Nuclear Medicine/PET, Children’s Hospital BostonHarvard Medical School
  • Royal Davis
    • Department of Radiology, Division of Nuclear Medicine/PET, Children’s Hospital BostonHarvard Medical School
  • S. Ted Treves
    • Department of Radiology, Division of Nuclear Medicine/PET, Children’s Hospital BostonHarvard Medical School
  • Frederick D. Grant
    • Department of Radiology, Division of Nuclear Medicine/PET, Children’s Hospital BostonHarvard Medical School
    • Department of Radiology, Division of Nuclear Medicine/PET, Children’s Hospital BostonHarvard Medical School
Original Article

DOI: 10.1007/s00259-008-0983-y

Cite this article as:
Zukotynski, K.A., Fahey, F.H., Laffin, S. et al. Eur J Nucl Med Mol Imaging (2009) 36: 602. doi:10.1007/s00259-008-0983-y

Abstract

Purpose

The aim of this study was to determine if warming patients prior to and during 18F-FDG uptake by controlling the room temperature could decrease uptake by brown adipose tissue (BAT).

Methods

A group of 40 children underwent 18F-FDG PET after being kept in the injection room at a constant temperature of 24°C for half an hour before and 1 hour after intravenous tracer administration. The rate of uptake by BAT in this group was compared to the uptake in a control group of 45 patients who underwent PET when the injection room temperature was 21°C.

Results

Uptake by BAT occurred in 5% of studies in the temperature-controlled room compared to 31% of studies performed when the injection room temperature was 21°C (p<0.002).

Conclusion

Maintaining room temperature at a constant 24°C, half an hour prior to and during the period of FDG uptake significantly decreases accumulation of FDG in BAT in children.

Keywords

Brown adipose tissue Temperature control Children PET

Copyright information

© Springer-Verlag 2008