Date: 12 Sep 2008

Respiratory motion handling is mandatory to accomplish the high-resolution PET destiny

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Positron emission tomography (PET) is an interesting metabolic imaging modality. Its strength relies mostly on its ability to quantify the measured metabolic signal. Recent developments with PET have enabled to reach the 2- to 5-mm full-width-at-half-maximum (FWHM) spatial resolution. With such an improvement, small amounts of motion during acquisition deteriorate the effective spatial resolution [1]. In order to take advantage of this wonderful recent amelioration in PET spatial resolution, it becomes critical to account for any intervening motion particularly respiratory motion, in order to minimize its effect on effective resolution. In the following, we will limit our editorial to respiratory motion, our subject of interest, and will not address other not specifically less important causes of motion, i.e., patient motion, cardiac contraction related motion, displacement of internal organs, and other physiologic organ motion (bowel, gallbladder ...). In the first part of the editori ...

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