Guidelines

European Journal of Nuclear Medicine and Molecular Imaging

, Volume 35, Issue 4, pp 851-885

EANM/ESC guidelines for radionuclide imaging of cardiac function

  • B. HesseAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of Copenhagen Email author 
  • , T. B. LindhardtAffiliated withDepartment of Cardiology, Hilleroed Hospital
  • , W. AcampaAffiliated withDepartment of Biomorphological and Functional Sciences, Institute of Biostructure and Bioimages of the National Council of Research, University of Naples Federico II
  • , C. AnagnostopoulosAffiliated withDepartment of Nuclear Medicine, Royal Brompton Hospital
  • , J. BallingerAffiliated withDepartment of Nuclear Medicine, Guy’s Hospital–Guy’s and St. Thomas’ Foundation Trust
  • , J. J. BaxAffiliated withDepartment of Cardiology, Leiden University Medical Center
  • , L. EdenbrandtAffiliated withDepartment of Clinical Sciences, Malmö, Lund University Research Program in Medical Informatics, Malmö University Hospital
  • , A. FlotatsAffiliated withNuclear Medicine Department, Autonomous University of Barcelona
  • , G. GermanoAffiliated withArtificial Intelligence Program at Cedars-Sinai Medical Center and Department of Medicine of the University of California at Los Angeles
    • , T. Gmeiner StoparAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenDepartment of Nuclear Medicine, University Medical Centre Ljubljana, Radiopharmacy and Clinical Biochemistry
    • , P. FrankenAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenNuclear Medicine, AZ VUB
    • , A. KelionAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenNuclear Medicine Department, Harefield Hospital
    • , A. KjaerAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of Copenhagen
    • , D. Le GuludecAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenService de medecine nucleaire, hôpital Bichat, APHP, Université Denis-Diderot, UMR577B, and Inserm U773
    • , M. LjungbergAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenMedical Radiation Physics, Clinical Sciences, Lund, Lund University
    • , A. F. MaenhoutAffiliated withDepartment of Nuclear Medicine, Royal Brompton Hospital
    • , C. MarcassaAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenDepartment of Cardiology, Fondazione Maugeri, IRCCS
    • , J. MarvingAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of Copenhagen
    • , F. McKiddieAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenNuclear Medicine Department, Aberdeen Royal Infirmary
    • , W. M. SchaeferAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenNuclear Medicine Department, University Hospital, Aachen University of Technology
    • , L. SteggerAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenDepartment of Nuclear Medicine, University Hospital Münster
    • , R. UnderwoodAffiliated withDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of CopenhagenDepartment of Nuclear Medicine, Royal Brompton Hospital

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Abstract

Radionuclide imaging of cardiac function represents a number of well-validated techniques for accurate determination of right (RV) and left ventricular (LV) ejection fraction (EF) and LV volumes. These first European guidelines give recommendations for how and when to use first-pass and equilibrium radionuclide ventriculography, gated myocardial perfusion scintigraphy, gated PET, and studies with non-imaging devices for the evaluation of cardiac function. The items covered are presented in 11 sections: clinical indications, radiopharmaceuticals and dosimetry, study acquisition, RV EF, LV EF, LV volumes, LV regional function, LV diastolic function, reports and image display and reference values from the literature of RVEF, LVEF and LV volumes. If specific recommendations given cannot be based on evidence from original, scientific studies, referral is given to “prevailing or general consensus”. The guidelines are designed to assist in the practice of referral to, performance, interpretation and reporting of nuclear cardiology studies for the evaluation of cardiac performance.

Keywords

Nuclear imaging EANM/ESC guidelines Cardiac function