Is PET-CT the only option?

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Accurate determination of the anatomic location of normal and pathological sites visualized on PET undoubtedly facilitates optimal interpretation of PET studies. It is now well established that image fusion with structural studies improves the diagnostic accuracy of images generated by PET [1]. PET images can be fused with CT and/or MRI either by using co-registration algorithms for PET and CT scans which have been acquired separately or by using combined PET-CT instruments. However, combined PET-CT scanners have certain advantages. Sequential acquisition of PET and CT images (one immediately after the other) minimizes patient and organ motion artifacts since the patient is positioned almost identically for both scans [2]. Furthermore, the CT data can be used for attenuation correction (AC) of the PET emission scan [3, 4]. Traditionally, an external radionuclide source has been employed for this purpose, but the use of CT for AC provides several advantages: First, the transmission scan