Date: 16 May 2006

Biological imaging for selecting and monitoring cancer therapy; a pathway to individualised therapy

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The 2005 report to the nation on the status of cancer, published in October 2005, indicates that during the past 20 years, cancer death rates for all cancer sites combined and for many common cancers have declined at the same time as the dissemination of guideline-based treatment in the community has increased [1]. The decline in world cancer death rates that began in the early 1990s occurred after more than six decades of reported increases in cancer mortality. Declines in overall cancer death rates occurred in both men and women, and for many of the 15 most common cancers, including cancer of the lung, colon, prostate and rectum in men, and cancers of the colon, rectum and breast in women. For many cancers these declines have occurred because of effective prevention and risk reduction interventions, screening and early detection and advances in both treatment and medical management. In addition, increasing knowledge linking tumor genetics with response to therapy have hel ...