European Journal of Nuclear Medicine and Molecular Imaging

, Volume 33, Issue 1, pp 81–86

Radiation exposure to family members of patients with thyrotoxicosis treated with iodine-131

  • Tone Cappelen
  • Jan Frede Unhjem
  • Anne Lise Amundsen
  • Gunnhild Kravdal
  • Ivar Følling
Original Article

DOI: 10.1007/s00259-005-1888-7

Cite this article as:
Cappelen, T., Unhjem, J.F., Amundsen, A.L. et al. Eur J Nucl Med Mol Imaging (2006) 33: 81. doi:10.1007/s00259-005-1888-7

Abstract

Purpose

The purpose of this study was twofold: (1) to measure the radiation exposure to family members of out-patients with thyrotoxicosis treated with radioiodine, 131I, using the recommendations from the European Commission (EC) guidance and age-specific periods for behaviour restrictions; (2) to use the results to identify necessary restrictions to ensure recommended dose constraints.

Methods

The study population comprised 76 family members (46 adults and 30 children below the age of 18) of 42 patients. The patients were treated with an average activity of 417 MBq (range 260–600 MBq). They received oral and written EC recommendations about behaviour restrictions (translated into Norwegian). On the day of treatment we repeated the oral instructions to the patient and an adult family member. The time periods for restrictions were 14 days for children aged 0–10 years, 7 days for persons aged 11–59 years and 3 days for persons aged 60 years and older. Family members wore a thermoluminescent dosimeter (TLD) on each wrist day and night for 2 weeks. The doses received were adjusted to give an estimate of the expected values if the TLDs had been worn indefinitely.

Results

Radiation doses well below the recommended dose constraints were measured for all adult family members and children, except one 2-year-old child; in the latter case the mother probably did not comply with the instructions given.

Conclusion

The radiation dose to family members of thyrotoxic patients treated with up to 600 MBq of radioiodine is well below recommended dose constraints if EC instructions are given and compliance is adequate. The duration of restrictions for various age groups used in this study may be considered when establishing guidelines in Norway.

Keywords

Iodine-131 therapyThyrotoxicosisRadiation protectionGuidelines

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Tone Cappelen
    • 1
  • Jan Frede Unhjem
    • 2
  • Anne Lise Amundsen
    • 1
  • Gunnhild Kravdal
    • 1
  • Ivar Følling
    • 3
  1. 1.Department of Clinical Chemistry and Nuclear Medicine, Akershus University HospitalUniversity of OsloOsloNorway
  2. 2.Norwegian Radiation Protection AuthorityØsteråsNorway
  3. 3.Section of Endocrinology, Akershus University HospitalUniversity of OsloOsloNorway