CASE REPORT

Skeletal Radiology

, Volume 28, Issue 3, pp 163-168

Vertebral involvement in SAPHO syndrome: MRI findings

  • A. NachtigalAffiliated withDepartment of Radiology, Hôpital Saint-Luc, Centre Hospitalier de l’Université de Montréal, 1058 St. Denis Street, Montreal, QC H2X 3J4, Canada
  • , E. CardinalAffiliated withDepartment of Radiology, Hôpital Saint-Luc, Centre Hospitalier de l’Université de Montréal, 1058 St. Denis Street, Montreal, QC H2X 3J4, Canada
  • , N. J. BureauAffiliated withDepartment of Radiology, Hôpital Saint-Luc, Centre Hospitalier de l’Université de Montréal, 1058 St. Denis Street, Montreal, QC H2X 3J4, Canada
  • , L. G. Sainte-MarieAffiliated withDepartment of Internal Medicine, Hôpital Saint-Luc, Centre Hospitalier de l’Université de Montréal, Québec,Canada
  • , F. MiletteAffiliated withDepartment of Pathology, Hôpital Saint-Luc, Centre Hospitalier de l’Université de Montréal, Québec,Canada

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Abstract 

We report on the MRI findings in the vertebrae and surrounding soft tissues in two patients with the SAPHO syndrome (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis). The MRI findings include abnormal bone marrow signal, either focal or diffuse, of the vertebral bodies and posterior elements; hyperintense paravertebral soft tissue swelling and abnormal signal of the intervertebral discs. These changes are consistent with discitis and osteitis.

Key words SAPHO syndrome Spine MRI Spondyloarthropathy Pustulosis