The diagnostic performance of radiography for detection of osteoarthritis-associated features compared with MRI in hip joints with chronic pain
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To evaluate the diagnostic performance of radiography for the detection of MRI-detected osteoarthritis-associated features in various articular subregions of the hip joint.
Materials and methods
Forty-four patients with chronic hip pain (mean age, 63.3 ± 9.5 years), who were part of the Hip Osteoarthritis MRI Scoring (HOAMS) cohort, underwent both weight-bearing anteroposterior pelvic radiography and 1.5 T MRI. The HOAMS study was a prospective observational study involving 52 subjects, conducted to develop a semiquantitative MRI scoring system for hip osteoarthritis features. In the present study, eight subjects were excluded because of a lack of radiographic assessment. On radiography, the presence of superior and medial joint space narrowing, superior and inferior acetabular/femoral osteophytes, acetabular subchondral cysts, and bone attrition of femoral head was noted. On MRI, cartilage, osteophytes, subchondral cysts, and bone attrition were evaluated in the corresponding locations. Diagnostic performance of radiography was compared with that of MRI, and the area under curve (AUC) was calculated for each pathological feature.
Compared with MRI, radiography provided high specificity (0.76–0.90) but variable sensitivity (0.44–0.78) for diffuse cartilage damage (using JSN as an indirect marker), femoral osteophytes, acetabular subchondral cysts and bone attrition of the femoral head, and a low specificity (0.42 and 0.58) for acetabular osteophytes. The AUC of radiography for detecting overall diffuse cartilage damage, marginal osteophytes, subchondral cysts and bone attrition was 0.76, 0.78, 0.67, and 0.82, respectively.
Diagnostic performance of radiography is good for bone attrition, fair for marginal osteophytes and cartilage damage, but poor for subchondral cysts.
- Zhang W, Doherty M. EULAR recommendations for knee and hip osteoarthritis: a critique of the methodology. Br J Sports Med. 2006;40:664–9. CrossRef
- Felson DT, Zhang Y. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis Rheum. 1998;41:1343–55. CrossRef
- Hoaglund FT, Steinbach LS. Primary osteoarthritis of the hip: etiology and epidemiology. J Am Acad Orthop Surg. 2001;9:320–7.
- Fortin PR, Clarke AE, Joseph L, et al. Outcomes of total hip and knee replacement: preoperative functional status predicts outcomes at six months after surgery. Arthritis Rheum. 1999;42:1722–8. CrossRef
- Altman R, Alarcon G, Appelrouth D, et al. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum. 1991;34:505–14. CrossRef
- Gossec L, Paternotte S, Bingham 3rd CO, et al. OARSI/OMERACT initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis. An OMERACT 10 Special Interest Group. J Rheumatol. 2011;38:1765–9. CrossRef
- Altman RD, Gold GE. Atlas of individual radiographic features in osteoarthritis, revised. Osteoarthr Cartil. 2007;15(Suppl A):A1–A56. CrossRef
- Wright AA, Cook C, Abbott JH. Variables associated with the progression of hip osteoarthritis: a systematic review. Arthritis Rheum. 2009;61:925–36. CrossRef
- Jacobsen S, Sonne-Holm S, Soballe K, Gebuhr P, Lund B. The relationship of hip joint space to self reported hip pain. A survey of 4.151 subjects of the Copenhagen City Heart Study: the Osteoarthritis Substudy. Osteoarthr Cartil. 2004;12:692–7. CrossRef
- Hayashi D, Xu L, Roemer FW, et al. Detection of osteophytes and subchondral cysts in the knee with use of tomosynthesis. Radiology. 2012;263:206–15. CrossRef
- Guermazi A, Hunter DJ, Roemer FW. Plain radiography and magnetic resonance imaging diagnostics in osteoarthritis: validated staging and scoring. J Bone Joint Surg Am. 2009;91 Suppl 1:54–62. CrossRef
- Hunter DJ, Arden N, Conaghan PG, et al. Definition of osteoarthritis on MRI: results of a Delphi exercise. Osteoarthr Cartil. 2011;19:963–9. CrossRef
- Roemer FW, Hunter DJ, Winterstein A, et al. Hip Osteoarthritis MRI Scoring System (HOAMS): reliability and associations with radiographic and clinical findings. Osteoarthr Cartil. 2011;19:946–62. CrossRef
- Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis. 1957;16:494–502. CrossRef
- Wiberg G. Studies on dysplastic acetabula and congenital subluxation of the hip joint. Acta Chir Scand. 1939;83 Suppl 58:5–135.
- Werner CM, Ramseier LE, Ruckstuhl T, et al. Normal values of Wiberg’s lateral center-edge angle and Lequesne’s acetabular index–a coxometric update. Skeletal Radiol. 2012;41:1273–8. CrossRef
- Tape TG (Accessed March 20, 2012.) The area under an ROC curve. Interpreting diagnostic tests. University of Nebraska Medical Center. Available at: http://gim.unmc.edu/dxtests/Default.htm
- Hunter DJ, Zhang YQ, Tu X, et al. Change in joint space width: hyaline articular cartilage loss or alteration in meniscus? Arthritis Rheum. 2006;54:2488–95. CrossRef
- Vignon E, Conrozier T, Piperno M, Richard S, Carrillon Y, Fantino O. Radiographic assessment of hip and knee osteoarthritis. Recommendations: recommended guidelines. Osteoarthr Cartil. 1999;7:434–6. CrossRef
- Amin S, LaValley MP, Guermazi A, et al. The relationship between cartilage loss on magnetic resonance imaging and radiographic progression in men and women with knee osteoarthritis. Arthritis Rheum. 2005;52:3152–9. CrossRef
- Goker B, Sancak A, Haznedaroglu S, Arac M, Block JA. The effects of minor hip flexion, abduction or adduction and X-ray beam angle on the radiographic joint space width of the hip. Osteoarthr Cartil. 2005;13:379–86. CrossRef
- Guermazi A, Roemer FW, Burstein D, Hayashi D. Why radiography should no longer be considered a surrogate outcome measure for longitudinal assessment of cartilage in knee osteoarthritis. Arthritis Res Ther. 2011;13:247. CrossRef
- Chan WP, Lang P, Stevens MP, et al. Osteoarthritis of the knee: comparison of radiography, CT, and MR imaging to assess extent and severity. AJR Am J Roentgenol. 1991;157:799–806. CrossRef
- Poleksic L, Zdravkovic D, Jablanovic D, Watt I, Bacic G. Magnetic resonance imaging of bone destruction in rheumatoid arthritis: comparison with radiography. Skeletal Radiol. 1993;22:577–80. CrossRef
- The diagnostic performance of radiography for detection of osteoarthritis-associated features compared with MRI in hip joints with chronic pain
Volume 42, Issue 10 , pp 1421-1428
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- 1. Quantitative Imaging Center, Department of Radiology, Boston University School of Medicine, FGH Building 3rd Floor, 820 Harrison Avenue, Boston, MA, 02118, USA
- 2. Department of Radiology, Beijing Jishuitan Hospital, Beijing, 100035, China
- 3. Department of Medicine, University of Sydney, Sydney, Australia
- 4. Division of Research, New England Baptist Hospital, Boston, MA, 02120, USA
- 5. Department of Radiology, Klinikum Augsburg, Augsburg, Germany
- 6. Department of Radiology, University of Erlangen, Erlangen, Germany