Skeletal Radiology

, Volume 41, Issue 3, pp 357–360

Magnetic resonance imaging appearance of scurvy with gelatinous bone marrow transformation

  • Christopher M. Brennan
  • Kristen A. Atkins
  • Colleen H. Druzgal
  • Cree M. Gaskin
Case Report

DOI: 10.1007/s00256-011-1350-9

Cite this article as:
Brennan, C.M., Atkins, K.A., Druzgal, C.H. et al. Skeletal Radiol (2012) 41: 357. doi:10.1007/s00256-011-1350-9

Abstract

Scurvy is a lethal but treatable disease that is rare in industrialized countries. Caused by vitamin C deficiency, it is most prevalent in persons of low socioeconomic status and smokers. Low levels of circulating vitamin C result in poor collagen fiber formation that, in turn, leads to demineralized bones, microfractures, and poor healing. Here we report a case of scurvy in a 5-year-old boy with normal radiographs in whom initial concern for leukemia based upon magnetic resonance imaging and clinical presentation led to a bone marrow biopsy revealing gelatinous transformation.

Keywords

ScurvyVitamin CMalnutritionMagnetic resonance imagingSerous atrophyGelatinous transformation

Copyright information

© ISS 2012

Authors and Affiliations

  • Christopher M. Brennan
    • 1
  • Kristen A. Atkins
    • 3
  • Colleen H. Druzgal
    • 4
  • Cree M. Gaskin
    • 1
    • 2
  1. 1.Department of Radiology and Medical ImagingUniversity of Virginia Health SystemCharlottesvilleUSA
  2. 2.Department of Orthopaedic SurgeryUniversity of Virginia Health SystemCharlottesvilleUSA
  3. 3.Department of PathologyUniversity of Virginia Health SystemCharlottesvilleUSA
  4. 4.Department of PediatricsUniversity of Virginia Health SystemCharlottesvilleUSA