Skeletal Radiology

, Volume 41, Issue 3, pp 357–360

Magnetic resonance imaging appearance of scurvy with gelatinous bone marrow transformation

Authors

  • Christopher M. Brennan
    • Department of Radiology and Medical ImagingUniversity of Virginia Health System
  • Kristen A. Atkins
    • Department of PathologyUniversity of Virginia Health System
  • Colleen H. Druzgal
    • Department of PediatricsUniversity of Virginia Health System
    • Department of Radiology and Medical ImagingUniversity of Virginia Health System
    • Department of Orthopaedic SurgeryUniversity of Virginia Health System
Case Report

DOI: 10.1007/s00256-011-1350-9

Cite this article as:
Brennan, C.M., Atkins, K.A., Druzgal, C.H. et al. Skeletal Radiol (2012) 41: 357. doi:10.1007/s00256-011-1350-9

Abstract

Scurvy is a lethal but treatable disease that is rare in industrialized countries. Caused by vitamin C deficiency, it is most prevalent in persons of low socioeconomic status and smokers. Low levels of circulating vitamin C result in poor collagen fiber formation that, in turn, leads to demineralized bones, microfractures, and poor healing. Here we report a case of scurvy in a 5-year-old boy with normal radiographs in whom initial concern for leukemia based upon magnetic resonance imaging and clinical presentation led to a bone marrow biopsy revealing gelatinous transformation.

Keywords

ScurvyVitamin CMalnutritionMagnetic resonance imagingSerous atrophyGelatinous transformation

Copyright information

© ISS 2012