Magnetic resonance imaging appearance of scurvy with gelatinous bone marrow transformation
First Online: 06 January 2012 Received: 19 October 2011 Revised: 08 December 2011 Accepted: 13 December 2011 DOI:
Cite this article as: Brennan, C.M., Atkins, K.A., Druzgal, C.H. et al. Skeletal Radiol (2012) 41: 357. doi:10.1007/s00256-011-1350-9 Abstract
Scurvy is a lethal but treatable disease that is rare in industrialized countries. Caused by vitamin C deficiency, it is most prevalent in persons of low socioeconomic status and smokers. Low levels of circulating vitamin C result in poor collagen fiber formation that, in turn, leads to demineralized bones, microfractures, and poor healing. Here we report a case of scurvy in a 5-year-old boy with normal radiographs in whom initial concern for leukemia based upon magnetic resonance imaging and clinical presentation led to a bone marrow biopsy revealing gelatinous transformation.
Keywords Scurvy Vitamin C Malnutrition Magnetic resonance imaging Serous atrophy Gelatinous transformation References
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