Angioleiomyoma: magnetic resonance imaging features in ten cases
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Angioleiomyoma is a rare, benign smooth muscle tumour arising from the tunica media of small veins and arteries and can occur anywhere in the body. The histological appearances are well documented, but there are relatively few descriptions of the magnetic resonance imaging (MRI) findings.
Materials and methods
A retrospective study of the clinical presentation, MRI appearances and histological findings of ten angioleiomyomas presenting as extremity soft tissue masses.
MRI typically demonstrated a well-defined, oval mass located superficial to the fascia with the commonest sites being the hand (three cases) and ankle/foot (five cases). The lesion was isointense to muscle on T1-weighted spin echo images with heterogeneous increased internal T2W/short tau inversion recovery (STIR) signal intensity, which commonly appeared as multiple linear or branching areas of hyperintensity. Enhancement after IV gadolinium ranged from diffuse to heterogeneous. In a single case, central fat signal intensity was seen, while a further case showed marked T2W/STIR hypointensity due to diffuse hyalinisation within the lesion.
This is the largest reported MRI series of extremity musculoskeletal angioleiomyoma. Angioleiomyoma should be considered in the differential diagnosis of a superficial mass in the hand or foot, particularly when characteristic linear or branching hyperintensity is seen on T2W or STIR images.
- Duhig, JT, Ayer, JP (1959) Vascular leiomyoma: a study of sixty-one cases. Arch Pathol 68: pp. 424-430
- Stout, AP (1937) Solitary cutaneous and subcutaneous leiomyoma. Am J Cancer 29: pp. 435-469
- Hachisuga, T, Hashimoto, H, Enjoji, M (1984) Angioleiomyoma: a clinicopathologic reappraisal of 562 cases. Cancer 54: pp. 126-130 CrossRef
- Calle, SC, Eaton, RG, Littler, JW (1994) Vascular leiomyomas in the hand. The J Hand Surg 19A: pp. 281-286 CrossRef
- Akizawa, S (1980) Angiomyoma: an analysis of 124 cases. Jikeikai Med 27: pp. 71-82
- Morimoto, N (1973) Angiomyoma (vascular leiomyoma): a clinicopathologic study. Med J Kagoshima Univ 24: pp. 663-683
- World Health Organization Classification of Tumours. Pathology & Genetics. Tumours of Soft Tissue and Bone. IARC Lyon, 2002.
- Hwang, JW, Ahn, JM, Kang, HS, Suh, JS, Kim, SM, Seo, JW (1998) Vascular leiomyoma of an extremity: MR imaging-pathology correlation. AJR Am J Roentgenol 171: pp. 981-985
- Lawson, GM, Salter, DM, Hooper, G (1995) Angioleiomyomas of the hand. A report of 14 cases. Journal of Hand Surgery 20B: pp. 479-483
- Freedman, AM, Meland, NB (1989) Angioleiomyomas of the extremities:report of a case and review of the Mayo Clinic experience. Plast Reconstr Surg 83: pp. 328-331 CrossRef
- Angioleiomyoma: magnetic resonance imaging features in ten cases
Volume 37, Issue 11 , pp 1003-1009
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- 1. Department of Radiology, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, HA7 4LP, UK
- 2. Department of Histopathology, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, HA7 4LP, UK