Skeletal Radiology

, Volume 33, Issue 11, pp 674–678

Xanthoma of the sacrum

  • Guo-Shu Huang
  • Chih-Wang Huang
  • Chian-Her Lee
  • John A. M. Taylor
  • Chih-Gueng Lin
  • Cheng-Yu Chen
Case Report

DOI: 10.1007/s00256-004-0829-z

Cite this article as:
Huang, GS., Huang, CW., Lee, CH. et al. Skeletal Radiol (2004) 33: 674. doi:10.1007/s00256-004-0829-z

Abstract

Xanthoma is a lesion containing abundant foamy histiocytes most commonly occurring in superficial soft tissues such as skin, subcutis, or tendon sheaths. The involvement of deep skeletal structures, however, is rare and has only been infrequently reported in the English literature. Most xanthomas occur in patients with hyperlipidemic disorders. We report a case of a xanthoma in the sacrum and ilium of a patient with hyperlipidemia type IIa, who had chronic lower back pain for more than 20 years. On radiographs the lesion appeared multiloculated and osteolytic with a thin sclerotic border and containing multiple nodular calcifications within its matrix. Computed tomographic images revealed a presacral soft-tissue mass that also infiltrated the adjacent sacroiliac joint and iliac fossa. On histologic examination, abundant areas of xanthoma cells and cholesterol clefts, typical of xanthoma, were present. The patient received simple curettage of the lesion, and his symptoms were markedly relieved.

Keywords

Xanthoma Sacrum Ilium Hyperlipidemia CT 

Copyright information

© ISS 2004

Authors and Affiliations

  • Guo-Shu Huang
    • 1
  • Chih-Wang Huang
    • 1
  • Chian-Her Lee
    • 2
  • John A. M. Taylor
    • 3
  • Chih-Gueng Lin
    • 4
  • Cheng-Yu Chen
    • 1
  1. 1.Department of Radiology, Tri-Service General HospitalNational Defense Medical CenterNeihu 114, TaipeiTaiwan, Republic of China
  2. 2.Department of Orthopedic Surgery, Tri-Service General HospitalNational Defense Medical CenterTaipeiTaiwan, Republic of China
  3. 3.Department of Clinical SciencesNew York Chiropractic CollegeSeneca FallsUSA
  4. 4.Department of Pathology, Tri-Service General HospitalNational Defense Medical CenterTaipeiTaiwan, Republic of China