Applied Microbiology and Biotechnology

, Volume 97, Issue 10, pp 4235–4241

Alternative splicing in ascomycetes


DOI: 10.1007/s00253-013-4841-x

Cite this article as:
Kempken, F. Appl Microbiol Biotechnol (2013) 97: 4235. doi:10.1007/s00253-013-4841-x


Alternative splicing is a complex and regulated process, which results in mRNA with different coding capacities from a single gene. Extend and types of alternative splicing vary greatly among eukaryotes. In this review, I focus on alternative splicing in ascomycetes, which in general have significant lower extend of alternative splicing than mammals. Yeast-like species have low numbers of introns and consequently alternative splicing is lower compared to filamentous fungi. Several examples from single studies as well as from genomic scale analysis are presented, including a survey of alternative splicing in Neurospora crassa. Another focus is regulation by riboswitch RNA and alternative splicing in a heterologous system, along with putative protein factors involved in regulation.


RegulationExtend and types of alternative splicingAscomycetesSpliceosome

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Abteilung für Botanische Genetik und Molekularbiologie, Botanisches Institut und Botanischer GartenChristian-Albrechts-Universität zu KielKielGermany