Applied Microbiology and Biotechnology

, Volume 77, Issue 3, pp 513–523

Yeast expression platforms

  • Erik Böer
  • Gerhard Steinborn
  • Gotthard Kunze
  • Gerd Gellissen
Mini-Review

DOI: 10.1007/s00253-007-1209-0

Cite this article as:
Böer, E., Steinborn, G., Kunze, G. et al. Appl Microbiol Biotechnol (2007) 77: 513. doi:10.1007/s00253-007-1209-0

Abstract

Yeasts provide attractive expression platforms. They combine ease of genetic manipulations and the option for a simple fermentation design of a microbial organism with the capabilities of an eukaryotic organism to secrete and to modify a protein according to a general eukaryotic scheme. For platform applications, a range of yeast species has been developed during the last decades. We present in the following review a selection of established and newly defined expression systems. The review is concluded by the description of a wide-range vector system that allows the assessment of the selected organisms in parallel for criteria like secretion or appropriate processing and modification in a given case.

Keywords

Heterologous gene expression Transformation Wide-range vector system Yeast expression platforms 

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Erik Böer
    • 1
  • Gerhard Steinborn
    • 1
  • Gotthard Kunze
    • 1
  • Gerd Gellissen
    • 2
  1. 1.Leibniz-Institut für Pflanzengenetik und KulturpflanzenforschungGaterslebenGermany
  2. 2.PharmedArtis GmbHAachenGermany