, Volume 56, Issue 9, pp 679–681

The EGF-TM7 family of the rat

Brief Communication

DOI: 10.1007/s00251-004-0729-3

Cite this article as:
Hamann, J. Immunogenetics (2004) 56: 679. doi:10.1007/s00251-004-0729-3


EGF-TM7 receptors are adhesion class heptahelical molecules predominantly expressed by cells of the immune system. Based on an analysis of the recently unraveled genome, the EGF-TM7 family of the rat is described here. Like the mouse, the rat has three EGF-TM7 receptors—CD97, EMR1 and EMR4. The highest conservation between the orthologues lies within the membrane-spanning part and emphasizes the functional importance of this region.


Adhesion classEGF-TM7 familyCD97EMRRat

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  1. 1.Laboratory for Experimental Immunology, G1-106, Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands