European Biophysics Journal

, Volume 41, Issue 1, pp 99–106

Colored noise in the fluctuations of an extended DNA molecule detected by optical trapping

  • Ignacio A. Martínez
  • Saurabh Raj
  • Dmitri Petrov
Original Paper

DOI: 10.1007/s00249-011-0763-7

Cite this article as:
Martínez, I.A., Raj, S. & Petrov, D. Eur Biophys J (2012) 41: 99. doi:10.1007/s00249-011-0763-7

Abstract

We studied fluctuations of an optically trapped bead connected to a single DNA molecule anchored between the bead and a cover glass or between two optically trapped beads. Power spectral densities of the bead position for different extensions of the molecule were compared with the power spectral density of the position fluctuations of the same bead without the molecule attached. Experiments showed that the fluctuations of the DNA molecule extended up to 80% by a force of 3 pN include the colored noise contribution with spectral dependence 1/fα with α ∼ 0.75.

Keywords

DNA Optical tweezers Colored noise Power spectral density 

Copyright information

© European Biophysical Societies' Association 2011

Authors and Affiliations

  • Ignacio A. Martínez
    • 1
  • Saurabh Raj
    • 1
  • Dmitri Petrov
    • 1
    • 2
  1. 1.ICFO—The Institute of Photonic SciencesCastelldefels, BarcelonaSpain
  2. 2.ICREA—Institucio Catalana de Recerca i Estudis AvancatsBarcelonaSpain

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