European Biophysics Journal

, Volume 37, Issue 1, pp 105–109

Amino acid partitioning using a Fiedler vector model

Biophysics Letter

DOI: 10.1007/s00249-007-0182-y

Cite this article as:
Shepherd, S.J., Beggs, C.B. & Jones, S. Eur Biophys J (2007) 37: 105. doi:10.1007/s00249-007-0182-y


This paper presents a new Fiedler vector model for categorising amino acids, which is based on the Miyazawa-Jernigan matrix. The model splits the amino acid residues into two hydrophobic groups (LFI) and (MVWCY) and two polar groups (HATGP) and (RQSNEDK). In so doing, it independently confirms the findings of Wang and Wang and Cieplak et al. and demonstrates the validity of using eigenvectors to partition amino acid groups.


Amino acidsResiduesPartitioningEigenvector Fiedler vector Peptide

Supplementary material

249_2007_182_MOESM1_ESM.doc (55 kb)
(DOC 55 kb)

Copyright information

© EBSA 2007

Authors and Affiliations

  1. 1.Medical Biophysics Group, School of Engineering, Design and TechnologyUniversity of BradfordBradfordUK
  2. 2.Division of Biomedical Sciences, School of Life SciencesUniversity of BradfordBradfordUK