Microbial Ecology

, Volume 63, Issue 3, pp 490–495

Diketopiperazines Produced by the Halophilic Archaeon, Haloterrigena hispanica, Activate AHL Bioreporters

  • Giuseppina Tommonaro
  • Gennaro Roberto Abbamondi
  • Carmine Iodice
  • Karen Tait
  • Salvatore De Rosa
Environmental Microbiology

DOI: 10.1007/s00248-011-9980-y

Cite this article as:
Tommonaro, G., Abbamondi, G.R., Iodice, C. et al. Microb Ecol (2012) 63: 490. doi:10.1007/s00248-011-9980-y
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Abstract

The generic term “quorum sensing” has been adopted to describe the bacterial cell-to-cell communication mechanism which coordinates gene expression when the population has reached a high cell density. Quorum sensing depends on the synthesis of small molecules that diffuse in and out of bacterial cells. There are few reports about this mechanism in Archaea. We report the isolation and chemical characterization of small molecules belonging to class of diketopiperazines (DKPs) in Haloterrigena hispanica, an extremely halophilic archaeon. One of the DKPs isolated, the compound cyclo-(l-prolyl–l-valine) activated N-acyl homoserine lactone (AHL) bioreporters, indicating that Archaea may have the ability to interact with AHL-producing bacteria within mixed communities.

Supplementary material

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Giuseppina Tommonaro
    • 1
  • Gennaro Roberto Abbamondi
    • 1
  • Carmine Iodice
    • 1
  • Karen Tait
    • 2
  • Salvatore De Rosa
    • 1
  1. 1.Institute of Biomolecular ChemistryCNR–National Research Council of ItalyPozzuoliItaly
  2. 2.Plymouth Marine LaboratoryPlymouthUK