Pediatric Radiology

, Volume 28, Issue 1, pp 23–29

Post-infectious bronchiolitis obliterans: clinical, radiological and pulmonary function sequelae

  • Anne B. Chang
  • John P. Masel
  • Brent Masters

DOI: 10.1007/s002470050286

Cite this article as:
Chang, A., Masel, J. & Masters, B. Pediatric Radiology (1998) 28: 23. doi:10.1007/s002470050286

Abstract

Background. There are few data on clinical, chest radiograph (CXR) or pulmonary function sequelae in children with post-infectious bronchiolitis obliterans (BO) (pulmonary crepitations, abnormalities on CXR, CT, nuclear medicine scans, or bronchography, with a history of past pulmonary infection and in the absence of other underlying pathology). Objective. To analyse the methodology of diagnosis, long-term clinical imaging and pulmonary function sequelae of post-infectious BO in children. Materials and methods. Imaging (CXRs, CT and nuclear lung scans) and clinical histories of 19 children were analysed. Results. Clinical follow-up (mean 6.8 years), revealed a high incidence of continuing problems (asthma and bronchiectasis). Fixed airway obstruction was the most common pulmonary function sequela. The sequelae on follow-up (mean 5.8 years) CXR were classified into five patterns which are illustrated: unilateral hyperlucency of an enlarged lung/part of lung; complete collapse of the affected lobe; unilateral hyperlucency of a small or normal-sized lung; bilateral hyperlucent lungs and a mixed pattern of persistent collapse, hyperlucency and peribronchial thickening. Conclusion. Long-term observations in children with post-infectious BO should be undertaken to detect bronchiectasis and obstructive airway disease. Sequelae evident on CXR, other than those previously described, can be found. Bronchography and/or lung biopsy are not usually required for the diagnosis of post-infectious BO.

Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • Anne B. Chang
    • 1
  • John P. Masel
    • 2
  • Brent Masters
    • 1
  1. 1.Mater Misericordiae Children's Hospital, South Brisbane, Queensland 4101, AustraliaAU
  2. 2.Royal Children's Hospital, Herston, Queensland 4029, AustraliaAU
  3. 3.Department of Respiratory Medicine, Mater Misericordiae Children's Hospital, South Brisbane, Queensland 4101, AustraliaAU