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Date: 27 Nov 2012
Tuberculous lymphadenopathy is not only obstructive but also inflammatory—it can erode anything it touches. Reply to Marchiori et al
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We thank Dr. Marchiori  and colleagues for taking an interest in our publication on lymphobronchial tuberculosis  and for contributing a case demonstrating the development of lymphobronchial fistula in a child with tuberculosis .
Members of our research group have reported the consequences of lymph node erosion into adjacent structures through inflammation and necrosis. These include erosion into the oesophagus [3, 4] with subsequent need for oesophageal stenting ; erosion into the pleural space with fibrin glue closure as a treatment option , erosion into the phrenic nerve with resulting palsy  and erosion into the thoracic duct causing chylothorax .
We have also performed a CT scan on a 5-month-old infant where the tuberculous lymphadenopathy eroded into the airway, leading to a significant amount of air detectable throughout the mediastinal structures and within the lymph nodes (Fig. 1). Bronchoscopy demonstrated a defect in the wall of the left lower lobe bro...
Marchiori E, Francisco FAF, Zanetti G et al (2012) Lymphobronchial fistula: another complication associated with lymphobronchial tuberculosis in children. Pediatr Radiol doi:10.1007/s00247-012-2538-4
- Tuberculous lymphadenopathy is not only obstructive but also inflammatory—it can erode anything it touches. Reply to Marchiori et al
Volume 43, Issue 2 , pp 254-255
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- Springer Berlin Heidelberg
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- 1. Department of Radiology, Faculty of Health Sciences, University of Witwatersrand, 7 York Road, Parktown, Johannesburg, 2001, South Africa
- 2. Department of Paediatrics, Stellenbosch University, Stellenbosch, South Africa