Pediatric Radiology

, Volume 43, Issue 2, pp 140–151

Rickets: Part I


DOI: 10.1007/s00247-012-2532-x

Cite this article as:
Shore, R.M. & Chesney, R.W. Pediatr Radiol (2013) 43: 140. doi:10.1007/s00247-012-2532-x


Rickets is characterized by impaired mineralization and ossification of the growth plates of growing children caused by a variety of disorders, the most frequent of which is nutritional deficiency of vitamin D. Despite ample knowledge of its etiology and the availability of cost-effective methods of preventing it, vitamin D deficiency rickets remains a significant problem in developing and developed countries. This two-part review covers the history, etiology, pathophysiology and clinical and radiographical findings of vitamin D deficiency rickets. Other less frequent causes of rickets and some of the disorders entering into the differential diagnoses of rickets are also considered. Controversial issues surrounding vitamin D deficiency include determination of what constitutes vitamin D sufficiency and the potential relationship between low levels of vitamin D metabolites in many individuals and unexplained fractures in infants.


RicketsVitamin DChildrenBoneMetabolic bone diseaseNon-accidental trauma

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Medical Imaging, Box 9Ann & Robert H. Lurie Children’s Hospital of ChicagoChicagoUSA
  2. 2.Department of RadiologyNorthwestern University Feinberg School of MedicineChicagoUSA
  3. 3.Department of Pediatrics, Le Bonheur Children’s HospitalUniversity of Tennessee Health Science CenterMemphisUSA