Pediatric Radiology

, Volume 42, Issue 4, pp 402-409

First online:

Pediatric MR elastography of hepatic fibrosis: principles, technique and early clinical experience

  • Larry A. BinkovitzAffiliated withDepartment of Radiology, Mayo Clinic Email author 
  • , Mounif El-YoussefAffiliated withPediatric Gastroenterology, Mayo Clinic
  • , Kevin J. GlaserAffiliated withDepartment of Radiology, Mayo Clinic
  • , Meng YinAffiliated withDepartment of Radiology, Mayo Clinic
  • , Anna K. BinkovitzAffiliated withMacalaster College
  • , Richard L. EhmanAffiliated withDepartment of Radiology, Mayo Clinic

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Numerous pediatric conditions result in hepatic fibrosis. As treatments develop for the underlying disorders, a non-invasive assessment of liver fibrosis would be beneficial as an adjunct or possible replacement for the traditional gold standard, liver biopsy. Magnetic resonance elastography is a noninvasive imaging technique that has been used successfully in adults for identification and assessment of liver fibrosis. This review describes the basic principles of MR elastography as well as the technical aspects specific to children. Clinical pediatric applications, limitations and areas for future research are described.


MR elastography Pediatric Liver MRE