Spinal dysraphism associated with the cutaneous lumbosacral infantile hemangioma: a neuroradiological review
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
Spinal dysraphism is suspected in patients with midline abnormalities, especially in those with lumbosacral cutaneous markings. A recent prospective study demonstrated that isolated cutaneous infantile hemangiomas (IH) of the lumbosacral region have one of the highest risks (relative risk of 438) of associated spinal dysraphism.
The specific types of dysraphism and radiological findings associated with cutaneous IH of the lumbosacral region have not been described in detail, to the best of our knowledge. The aim of this multicenter study is to retrospectively classify types of spinal anomalies associated with the cutaneous lumbosacral IH.
Materials and methods
The radiological images of 20 cases of lumbosacral infantile hemangioma associated with spinal dysraphism were reviewed.
Tethered cord was found in 60% of the 20 cases, spinal lipoma was present in 50% and 45% had intraspinal hemangiomas. Sinus tract was found in 40% of the children.
A range of spinal anomalies is associated with cutaneous lumbosacral infantile hemangiomas and MRI can be used to characterize these abnormalities.
- Drolet BA, Chamlin SL, Garzon MC et al (2010) Prospective study of spinal anomalies in children with infantile hemangiomas of the lumbosacral skin. J Pediatr 157:789–794 CrossRef
- Guggisberg D, Hadj-Rabia S, Viney C et al (2004) Skin markers of occult spinal dysraphism in children: a review of 54 cases. Arch Dermatol 140:1109–1115 CrossRef
- Goldberg NS, Hebert AA, Esterly NB (1986) Sacral hemangiomas and multiple congenital abnormalities. Arch Dermatol 122:684–687 CrossRef
- Albright AL, Gartner JC, Wiener ES (1989) Lumbar cutaneous hemangiomas as indicators of tethered spinal cords. Pediatrics 83:977–980
- Girard C, Bigorre M, Guillot B et al (2006) PELVIS syndrome. Arch Dermatol 142:884–888 CrossRef
- Stockman A, Boralevi F, Taieb A et al (2007) SACRAL syndrome: spinal dysraphism, anogenital, cutaneous, renal and urologic anomalies, associated withangioma of lumbosacral localization. Dermatology 214:40–45 CrossRef
- Iaocobas I, Burrows PE, Frieden IJ et al (2010) LUMBAR: association between cutaneous infantile hemangiomas of the lower body and regional congenital anomalies. J Pediatr 157:795–801 CrossRef
- Kriss VM, Desai NS (1998) Occult spinal dysraphism in neonates: assessment of high risk cutaneous stigmata on sonography. AJR 171:1687–1692
- Hoffman HJ, Hendrick EB, Humphreys RP (1976) The tethered spinal cord: its protean manifestations, diagnosis and surgical correction. Childs Brain 2:145–155
- Yamada S, Won DJ, Pezeshkpour G et al (2007) Pathophysiology of tethered cord syndrome and similar complex disorders. Neurosurg Focus 23:E6 CrossRef
- Hajnovic L, Trnka J (2007) Tethered spinal cord syndrome—the importance of time for outcomes. Eur J Pediatr Surg 17:190–193 CrossRef
- Muthukumar N (2009) Congenital spinal lipomatous malformations. Part I-Classification. Acta Neurochir 151:179–188 CrossRef
- Muthukumar N (2009) Congenital spinal lipomatous malformations. Part II-Clinical presentation, operative findings, and outcome. Acta Neurochir 151:189–197 CrossRef
- Karikari IO, Selznick LA, Cummings TJ et al (2007) Spinal capillary hemangioma in infants: report of two cases and review of the literature. Pediatr Neurosurg 43:125–129 CrossRef
- Martinez-Niguez JF, Almagro MJ, Ferri-Niguez B et al (2011) Spinal dermal sinus and pseudo-dermal sinus tracts: two different entities. Childs Nerv Syst 27:609–616 CrossRef
- Hess CP, Fullerton HJ, Metry DW et al (2010) Cervical and intracranial arterial anomalies in 70 patients with PHACE syndrome. AJNR 31:1980–1986 CrossRef
- Spinal dysraphism associated with the cutaneous lumbosacral infantile hemangioma: a neuroradiological review
Volume 42, Issue 3 , pp 315-320
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Spinal dysraphism
- Industry Sectors
- Author Affiliations
- 1. Departments of Dermatology and Pediatrics, Children’s Hospital of Wisconsin, Medical College of Wisconsin, P. O. Box 1997, Milwaukee, WI, 53201-1997, USA
- 2. Department of Pediatric Radiology, Children’s Hospital of Wisconsin, Milwaukee, WI, USA
- 3. Section of Dermatology, Children’s Mercy Hospital and Clinics, Kansas City, MO, USA
- 4. Department of Dermatology, Baylor College of Medicine, Houston, TX, USA
- 5. Departments of Dermatology and Pediatrics, Columbia University, New York, NY, USA
- 6. Departments of Pediatrics and Dermatology, Children’s Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
- 7. Department of Dermatology, University of California at San Francisco, San Francisco, CA, USA