Cervical spinal canal compromise in a 14-year-old girl with hereditary multiple exostoses
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- Patel, A. & Thacker, M.M. Pediatr Radiol (2010) 40: 158. doi:10.1007/s00247-010-1751-2
Multiple hereditary exostoses is an autosomal-dominant disorder characterized by the development of multiple cartilage-capped lesions in rapidly growing bone. The cervical spine represents 80% of spine involvement with C2 being the most commonly affected vertebra . Most osteochondromas arise from the posterior elements of the vertebra and do not encroach on the spinal canal. A recent study reported a 68% prevalence of spinal involvement with 27% having lesions encroaching on the spinal canal in 44 patients with multiple hereditary exostoses . Some patients may develop acute neurological deficits. A treating physician’s awareness of this high prevalence is essential.