Pediatric Radiology

, 39:117

Chest radiological patterns predict the duration of mechanical ventilation in children with RSV infection

  • Parthak Prodhan
  • Sjirk J. Westra
  • James Lin
  • Sarit Karni-Sharoor
  • Susan Regan
  • Natan Noviski
Original Article

DOI: 10.1007/s00247-008-1042-3

Cite this article as:
Prodhan, P., Westra, S.J., Lin, J. et al. Pediatr Radiol (2009) 39: 117. doi:10.1007/s00247-008-1042-3



RSV-infected children demonstrate various radiographic features, some of which are associated with worse clinical outcomes.


To investigate whether specific chest radiological patterns in RSV-infected children with acute respiratory failure (ARF) in the peri-intubation period are associated with prolonged duration of mechanical ventilation.

Materials and methods

We included RSV-infected children <1 year of age admitted with ARF from 1996 through 2002 to the pediatric intensive care unit at Massachusetts General Hospital. Their chest radiographs were evaluated at three time-points: preintubation (day −1) and days 1 and 2 after intubation. Univariate and multiple logistic regressions models were utilized to investigate our objective.


The study included 46 children. Using day 1 chest radiograph findings to predict duration of mechanical ventilation of >8 days, a backward stepwise regression arrived at a model that included age and right and left lung atelectasis. Using day 2 chest radiograph results, the best model included age and left lung atelectasis. A model combining the two days’ findings yielded an area under the ROC curve of 0.92 with a satisfactory fit (P = 0.95).


Chest radiological patterns around the time of intubation can identify children with RSV-associated ARF who would require prolonged mechanical ventilation.


RSV infection Pediatric ICU Mechanical ventilation Chest radiograph Outcome 

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Parthak Prodhan
    • 1
  • Sjirk J. Westra
    • 2
  • James Lin
    • 3
  • Sarit Karni-Sharoor
    • 4
  • Susan Regan
    • 5
  • Natan Noviski
    • 6
  1. 1.Division of Pediatric Critical Care and Cardiology, College of MedicineUniversity of Arkansas for Medical SciencesLittle RockUSA
  2. 2.Division of Pediatric RadiologyMassachusetts General HospitalBostonUSA
  3. 3.Division of Pediatric Critical CareMattel Children’s Hospital at UCLALos AngelesUSA
  4. 4.Pediatric Critical Care UnitShaarei Tzedek Medical CenterJerusalemIsrael
  5. 5.Department of MedicineMassachusetts General HospitalBostonUSA
  6. 6.Pediatric Critical Care MedicineMassachusetts General HospitalBostonUSA

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