Pediatric Cardiology

, Volume 32, Issue 5, pp 628–633

Cross-Sectional Analysis of Cardiovascular Risk Factors in Children With Parental History of Premature Ischemic Heart Disease

Authors

  • Gal Neuman
    • Department of PediatricsMeyer Children’s Hospital
    • Technion Faculty of Medicine
    • Department of PediatricsMeyer Children’s Hospital
    • Technion Faculty of Medicine
  • Doron Aronson
    • Technion Faculty of Medicine
    • Department of CardiologyRambam Health Care Campus
  • Avraham Lorber
    • Technion Faculty of Medicine
    • Department of Pediatric CardiologyMeyer Children’s Hospital
  • Diana Gaitini
    • Technion Faculty of Medicine
    • Department of Medical ImagingRambam Health Care Campus
  • Roy Onn
    • Department of PediatricsMeyer Children’s Hospital
    • Technion Faculty of Medicine
  • Naim Shehadeh
    • Department of PediatricsMeyer Children’s Hospital
    • Technion Faculty of Medicine
Original Article

DOI: 10.1007/s00246-011-9931-x

Cite this article as:
Neuman, G., Shavit, I., Aronson, D. et al. Pediatr Cardiol (2011) 32: 628. doi:10.1007/s00246-011-9931-x

Abstract

This study aimed to evaluate the presence of cardiovascular risk factors in children with a parental history of premature ischemic heart disease (two- or three-vessel disease diagnosed before the age of 55 in men and 65 in women). A prospective cross-sectional study was performed on 55 children. The following parameters were assessed: body mass index (BMI), waist and hip circumference, blood pressure, lipids profile, fasting glucose (FG), C-reactive protein (CRP), and carotid intimal-medial thickness (CIMT). Twenty-eight children had hypercholesterolemia, and 11 had other forms of dyslipidemia. Sixteen children had a high BMI; 17 had increased CRP levels; 2 were hypertensive; and 2 had impaired FG. CIMT levels were not correlated with age (Pearson r = −0.486; p = 0.78) and height (Pearson r = −6.31; p = 0.84), but they were correlated with cholesterol levels (Spearman r = 0.375; p < 0.005). Most patients (83%) had ≥2 risk factors; half of them had ≥3 risk factors. We concluded that these at-risk children should be carefully screened for all known risk factors.

Keywords

Ischemic heart disease Cardiovascular disease Risk factors Children Parental

Copyright information

© Springer Science+Business Media, LLC 2011