\( {V}_{\text{O}_{2}}\) @RER_{1.0} : A Novel Submaximal Cardiopulmonary Exercise Index
 Clifford Chin,
 Jeffrey Kazmucha,
 Nancy Kim,
 Reny Suryani,
 Inger Olson
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Maximal oxygen consumption (\( \dot{V}_{\text{O}_{2}}\text{max}\)) is the “gold standard” by which to assess functional capacity; however, it is effort dependent. \(\text{V}_{\text{O}_{2}}\)@RER_{1.0} is defined when \(\text{V}_{\text{O}_{2}}={V}_{\text{CO}_{2}}\). Between December 22, 1997 and November 9, 2004, 305 pediatric subjects underwent cycle ergometer cardiopulmonary exercise testing, exercised to exhaustion, and reached a peak respiratory exchange ratio ≥1.10. Group 1 subjects achieved a peak \(\text{V}_{\text{O}_{2}} \ge 80\%\) of predicted \( \dot{V}_{\text{O}_{2}}\text{max}\); group 2 subjects achieved a peak \(\text{V}_{\text{O}_{2}} \le 60\% \) of predicted \( \dot{V}_{\text{O}_{2}}\text{max}\); and group 3 subjects achieved a peak \(\text{V}_{\text{O}_{2}}\) between 61 and 79% of predicted \( \dot{V}_{\text{O}_{2}}\text{max}\). Linear regression analysis was performed for \(\text{V}_{\text{O}_{2}}\)@RER_{1.0} as a function of predicted \( \dot{V}_{\text{O}_{2}}\text{max}\) for group 1 subjects. A −2 SD regression line and equation was created. \( \text{V}_{\text{O}_{2}}\)@RER_{1.0} data from groups 2 and 3 were plotted onto the normative graph. Contingency table and relativerisk analysis showed that an abnormal \( \text{V}_{\text{O}_{2}}\)@RER_{1.0} predicted an abnormal peak \(\text{V}_{\text{O}_{2}}\)(positivepredictive value 83%, negativepredictive value 85%, sensitivity 84%, and specificity 84%). \( \text{V}_{\text{O}_{2}}\)@RER_{1.0} is a highly sensitive, specific, and predictive submaximal index of functional capacity. This submaximal index is easy to identify without subjectivity. This index may aid in the evaluation of subjects who cannot exercise to maximal parameters.
 Title
 \( {V}_{\text{O}_{2}}\) @RER_{1.0}: A Novel Submaximal Cardiopulmonary Exercise Index
 Journal

Pediatric Cardiology
Volume 31, Issue 1 , pp 5055
 Cover Date
 201001
 DOI
 10.1007/s0024600995449
 Print ISSN
 01720643
 Online ISSN
 14321971
 Publisher
 SpringerVerlag
 Additional Links
 Topics
 Keywords

 Exercise
 Submaximal exercise
 Pediatrics
 Industry Sectors
 Authors

 Clifford Chin ^{(1)}
 Jeffrey Kazmucha ^{(2)}
 Nancy Kim ^{(1)}
 Reny Suryani ^{(3)}
 Inger Olson ^{(1)}
 Author Affiliations

 1. Division of Pediatric Cardiology, Stanford University, Palo Alto, CA, 94304, USA
 2. Pediatric Heart Center, Lucile Packard Children’s Hospital at Stanford, Palo Alto, CA, 94304, USA
 3. Monash Medical Centre, University of Melbourne, Melbourne, VIC, 3800, Australia