Article

Pediatric Cardiology

, Volume 26, Issue 4, pp 344-349

First online:

Vascular Tumors of the Heart in Infants and Children: Case Series and Review of the Literature

  • A.S. MackieAffiliated withDepartment of Cardiology, Children's Hospital Boston, Harvard Medical SchoolDivision of Cardiology, Room D-371, Montreal Children's Hospital Email author 
  • , H.P.W. KozakewichAffiliated withDepartment of Pathology, Children's Hospital Boston, Harvard Medical School
  • , T. GevaAffiliated withDepartment of Cardiology, Children's Hospital Boston, Harvard Medical School
  • , A.R. Perez-AtaydeAffiliated withDepartment of Pathology, Children's Hospital Boston, Harvard Medical School
  • , J.B. MullikenAffiliated withDivision of Plastic Surgery, Children's Hospital Boston, Harvard Medical School

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Abstract

Primary tumors of the heart are rare in children, of which vascular tumors comprise a small subgroup. We present the clinical, histopathologic, and imaging findings in six children with vascular tumors of the heart and review the findings of 36 previously published cases. We observed three intramuscular hemangiomas of the small-vessel type in older children, two congenital hemangiomas in infants, and one malignant polymorphous hemangioendothelioma. Intramuscular hemangiomas did not respond to corticosteroid and were biologically distinct from the congenital hemangiomas, both of which exhibited regression with pharmacotherapy. Age at diagnosis appears to predict histologic type, tumor location, and clinical presentation.

Keywords

Heart Vascular neoplasms