Urological Research

, Volume 29, Issue 2, pp 118–125

Clinical options for imipramine in the management of urinary incontinence

Authors

  • J. M. Hunsballe
    • International Enuresis Research Centre at the Institute of Experimental Clinical Research, University of Aarhus, Skejby University Hospital, Brendstrupgaardvej 8200 Aarhus N, Denmark e-mail: janjen@mail.tele.dk; Fax: +45 89496011
  • J. C. Djurhuus
    • International Enuresis Research Centre at the Institute of Experimental Clinical Research, University of Aarhus, Skejby University Hospital, Brendstrupgaardvej 8200 Aarhus N, Denmark e-mail: janjen@mail.tele.dk; Fax: +45 89496011
ORIGINAL PAPER

DOI: 10.1007/s002400100175

Cite this article as:
Hunsballe, J. & Djurhuus, J. Urological Research (2001) 29: 118. doi:10.1007/s002400100175

Abstract

Urinary incontinence is a common disorder in both childhood and adulthood. Proper treatment depends on insight into the pathophysiology and pharmacology of the lower urinary tract. This article reviews the mechanism of action of an old but commonly used drug, the tricyclic antidepressant agent imipramine, in nocturnal enuresis and stress and urge incontinence with reference to neuropharmacology and the relevant pathophysiology.

Key words ImipramineIncontinenceTreatmentTricyclic antidepressantsUrinary

Copyright information

© Springer-Verlag Berlin Heidelberg 2001