PAEDIATRIC NEURORADIOLOGY

Neuroradiology

, Volume 43, Issue 10, pp 868-874

First online:

An unusual cystic appearance of disseminated low-grade gliomas

  • T. HuangAffiliated withDepartment of Radiology, The Children's Hospital of Philadelphia, 34th St. & Civic Center Blvd., Philadelphia, PA 19104, USA Tel.: + 1-2 15-5 90 10 30 Fax: + 1-2 15-5 90 13 45
  • , R. A. ZimmermanAffiliated withDepartment of Radiology, The Children's Hospital of Philadelphia, 34th St. & Civic Center Blvd., Philadelphia, PA 19104, USA Tel.: + 1-2 15-5 90 10 30 Fax: + 1-2 15-5 90 13 45
  • , G. PerilongoAffiliated withDipartimento di Pediatria, 2 n Clinica Pediatrica e Centro Leucemie Infantili, Regione Veneto, Azienda Ospedaliera di Padova, Universita di Padova, Via Giustiniani 3, 35 128 Padua, Italy
  • , B. A. KaufmanAffiliated withDepartment of Neurosurgery, St Louis Children's Hospital, One Children's Place, St Louis, MO 63110–1077, USA
  • , K. R. HoldenAffiliated withDivision of Pediatric Neurology, Room 511, Children's Hospital, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425–2232, USA
  • , C. CarolloAffiliated withDivision of Neuroradiology, Regione Veneto, Azienda Ospedalieri di Padova, Universita di Padova, Via Giustiniani 3, 35 128 Padua, Italy
  • , W. K. “Kling” ChongAffiliated withDepartment of Radiology, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK

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Abstract

We report five cases of pediatric disseminated low-grade gliomas of the brainstem or spinal cord that exhibited an unusual, cystic pattern. Leptomeningeal disease was present in three of these at diagnosis, and was detected shortly afterwards in the other two. Four patients are alive up to 5 years later, following minimal to no intervention, while one is dead.

Keywords Gliomas Low-grade Disseminated Leptomeningeal metastases Cysts