Neuroradiology

, Volume 41, Issue 12, pp 943–945

Sydenham's chorea: MRI and proton spectroscopy

  • M. Castillo
  • L. Kwock
  • A. Arbelaez
PAEDIATRIC NEURORADIOLOGY

DOI: 10.1007/s002340050872

Cite this article as:
Castillo, M., Kwock, L. & Arbelaez, A. Neuroradiology (1999) 41: 943. doi:10.1007/s002340050872

Abstract

We present the MRI and proton spectroscopy findings in a child with clinical diagnosis of Sydenham's chorea. MRI showed high signal in the caudate nuclei and putamina on T2-weighted images. We believe that the spectra showed an abnormality in the number and/or function of neurons, lipids from cellular breakdown (cytolytic effect of antibodies), aminoacids (related to the presence of antibodies in the neostriatum), and sugars (also related to the presence of antibodies). The spectroscopy features correlate well with the histopathology and biochemistry of this rare disorder.

Key words Chorea Sydenham's Magnetic resonance imaging Magnetic resonance spectroscopy 

Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • M. Castillo
    • 1
  • L. Kwock
    • 1
  • A. Arbelaez
    • 1
  1. 1.Department of Radiology, CBF7510 University of North Carolina School of Medicine, Chapel Hill, NC 27599-7510, USA e-mail: castillo@med.unc.edu, Tel.: + 1-9 19-9 66-30 87, Fax: + 1-9 19-9 66-19 94US

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