Neuroradiology

, Volume 41, Issue 9, pp 657–665

The prevalence and distribution of white-matter changes on different MRI pulse sequences in a post-stroke cohort

  • R. Mäntylä
  • H. J. Aronen
  • O. Salonen
  • M. Korpelainen
  • T. Peltonen
  • C.-G. Standertskjöld-Nordenstam
  • T. Erkinjuntti
DIAGNOSTIC NEURORADIOLOGY

DOI: 10.1007/s002340050820

Cite this article as:
Mäntylä, R., Aronen, H., Salonen, O. et al. Neuroradiology (1999) 41: 657. doi:10.1007/s002340050820

Abstract

No uniform criteria currently exist for rating white-matter (WM) high-signal foci on MRI. Ratings are based on descriptive terms, different pulse sequences and different WM areas. Reports on the prevalence and clinical correlates of high-signal foci have been contradictory. We wanted to examine the contribution of the pulse sequence and WM area on rating WM changes. We analysed WM changes separately on T2-, protondensity (PD)- and T1-weighted images in periventricular, subcortical, watershed area and deep WM. The difference between T2- and PD-weighted images was significant for frontal caps, counting small foci or analysing subcortical changes. T1-weighted images showed significantly less change, but the number of foci detected was greater than previously thought. The prevalence of WM high-signal foci was greatest in the watershed zone and smallest in the subcortical area. There was a significant correlation between foci in different areas.

Key words Magnetic resonance imagingIschaemia cerebralWhite matter

Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • R. Mäntylä
    • 1
  • H. J. Aronen
    • 1
  • O. Salonen
    • 1
  • M. Korpelainen
    • 1
  • T. Peltonen
    • 1
  • C.-G. Standertskjöld-Nordenstam
    • 1
  • T. Erkinjuntti
    • 2
  1. 1.Department of Radiology, University of Helsinki, Haartmaninkatu 4, FIN-00290 Helsinki, Finland Tel.: + 358-9-4717 2479, Fax: + 358-9-4717 44 04, e-mail: riitta.mantyla@helsinki.fiFI
  2. 2.Department of Clinical Neurosciences, Memory Research Unit, Helsinki University Central Hospital, Helsinki, FinlandFI