, Volume 42, Issue 2, pp 81–84

How often is haemosiderin not visible on routine MRI following traumatic intracerebral haemorrhage?

  • J. M. Wardlaw
  • P. F. X. Statham

DOI: 10.1007/s002340050019

Cite this article as:
Wardlaw, J. & Statham, P. Neuroradiology (2000) 42: 81. doi:10.1007/s002340050019


Intracerebral haemorrhage may be visible indefinitely on MRI, due to persistence of haemosiderin in macrophages around the lesion, but it is not clear whether all haemorrhages produce haemosiderin or, if not, what proportion cannot be identified as former haemorrhages on routine MRI. We performed routine MRI (spin-echo T2- and proton-density weighted images) in 116 survivors of moderate to severe head injury, 1–5 years after injury. We reviewed the images blindly and correlated them with CT in the acute stage, to determine how many haemorrhages from the acute stage were identifiable by virtue of haemosiderin deposition on late MRI. Of 106 haemorrhages in 78 patients on CT at the time of injury, 96 (90 %) were visible as haemosiderin on late MRI. Of the old haemorrhages without haemosiderin, seven of ten were in patients where another haemorrhage with haemosiderin was still visible elsewhere in the brain. No patient or haemorrhage features explained the formation or absence of haemosiderin. Thus about 10 % of definite haematomas show no trace of haemosiderin on routine spin-echo MRI. Radiologists should be alerted to supplement routine spin-echo with gradient-echo sequences if there is a reason to suspect, or specifically exclude, prior haemorrhage.

Key words Haemorrhage, intracerebral Haemosiderin Magnetic resonance imaging 

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • J. M. Wardlaw
    • 1
  • P. F. X. Statham
    • 1
  1. 1.Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK e-mail:, Tel.: 01 31 5 37 29 43, Fax: 01 31 3 32 51 50GB